Based on my research, various drugs ranked in order of danger...

Most Dangerous from Worst to Least

#1 Meth
#2 Nicotine
#3 Heroin
#4 Crack
#5 Alcohol
#6 Powder Cocaine
#7 Opium
#8 Caffine
#9 Natural Stuff (Shrooms & Psilocybin etc..)
#10 Weed