Wow 5-htp shown to lessen THC induced memory loss

"Studies have also indicated miscellaneous benefits from 5-HTP supplementation in patients with fibromyalgia. Reductions in serotonergic tone are partially responsible for cognitive deficits (memory loss) resulting from tetrahydrocannibinol (THC, the active component in marijuana). When given to rats, 5-HTP can significantly attenuate THC-induced memory impairment.[3]"

This is from this page http://en.wikipedia.org/wiki/5htp

http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract
Department of Physiology and Pharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Japan.

"The present study investigated the involvement of the serotonin (5-hydroxytryptamine, 5-HT) neuronal system in the Delta(9)-tetrahydrocannabinol-induced impairment of spatial memory in the eight-arm radial maze in rats. Delta(9)-Tetrahydrocannabinol (6 mg/kg, i.p.), which impairs spatial memory, significantly increased the 5-HT content in the ventral hippocampus. A microdialysis study showed that Delta(9)-tetrahydrocannabinol (6 mg/kg, i.p.) decreased 5-HT release in the ventral hippocampus. The 5-HT precursor, 5-hydroxy-L-tryptophan (5-HTP; 50 mg/kg, i.p.), the 5-HT re-uptake inhibitor, clomipramine (0.01 and 0.1 mg/kg, i.p.), the 5-HT receptor agonist, 5-methoxy-N,N-dimethyltryptamine (5-MeODMT; 0.01 and 0.03 mg/kg, i.p.), and the 5-HT(2) receptor agonist, 1-(2,5-dimethoxy 4-iodophenyl)-2-amino propane (DOI; 10 microg/kg, i.p.), significantly attenuated the Delta(9)-tetrahydrocannabinol-induced impairment of spatial memory. These results suggest that the 5-HT neuronal system may be involved in the Delta(9)-tetrahydrocannabinol-induced impairment of spatial memory.

PMID: 12079687 [PubMed - indexed for MEDLINE]"

So where does one get ahold of this 'so-called' 5-htp?

What were we talking about?


:jointsmile:

TGF

Try your local health food store.

I picked some up at wal-mart. Cost $7.69 for 45 50mg gel caps. I took 2 of them at 4:00, from what I read it takes about an hour and a half to reach full effectiveness. I'll smoke a bowl then and report back to you :)

You people are crazy,,,if yor not happy with pot,,,stop smoking it...

damn thanks for the info. im gonna get some of that shit and give a couple week test run to see if it affects my memory whatsoever.

I love pot but nothing in this world is perfect... a little memory loss attributed to smoking weed's not gonna make me quit but if i can help reduce/stop it, of course im going to try!

forgetting stuff is half the fun of being stoned out of your mind

I forgot what I was going to write, and I 'm not stoned.

Oh yeah, now I remember. I started taking 5-HTP recently.

Quote:

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Originally Posted by Skink

You people are crazy,,,if yor not happy with pot,,,stop smoking it...

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Its not even like that skink. 5-htp also increases your high. It does so because 5-htp is used by the brain in the production of serotonin.

How you feeling splifted?