Researchers Find Cannabis Can Strengthen Bones

Researchers at Hebrew University have found that extracts from the cannabis plant can help strengthen human bones, preventing osteoporosis, according to an Israel21c report.



An article on the Hebrew University research appeared this week in the prestigious American PNAS (Proceedings of the National Academy of Sciences of the U.S.A.) journal. The research team, headed by Prof. Itai Bab, worked in Hebrew University's bone laboratory.

Substances produced mainly in the brain, called endocannabinoids, are made of fatty acids and exist in the bone and elsewhere. The substances bind to and activate two receptors - CB1 in the nervous system and CB2 in the immune system.

A high number of CB2-receptors were found in the bones of the mice and shown to be essential in preserving normal bone density. Mice lacking those receptors were shown to develop osteoporosis as they age.

Osteoporosis, a common ailment in the Western world, can lead to easily broken bones and disabilities.

The study shows that plants such as cannabis, which contain substances that activate CB2 receptors, can be used as a basis of drugs to help those suffering from osteoporosis. The researchers have developed a synthetic compound called HU-308 which succeeds in combatting osteoporosis in mice.

Though the cannabis plant is known mostly for marijuana, which comes from the flowers of the female plants, the extracts have no psychoactive side effects.


http://www.israelnationalnews.com/news.php3?id=96146

extracts no psychoactive effects????
I'll never buy hash again :-)

When will HU-308 be available for human studies? I would be willing to review the case studies and if favorable to my needs become a test subject. Thank you. If you have any other information and/or sites related to bone loss please e-mail me. Do you know or can you refer me to a Doctor on the west side of Washington. I don't like to drive-or even go to the larger cities. Thanks again klh/kburnt86

It's funny. The more science finds out about cannabinoid receptors, the more we try to emulate them.