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I use a perpetual system.
I find the advantages are:
Consistent, fresh medicine
Harvest involves minutes instead of hours.
Drying is easier.
Odor is more consistent.
Can have many different strains at the same time.
With my States plant requirement, it seems the only viable way for me to not get low or have stale meds.
The only real benefit for cycling is its easier to clean out the room once in awhile. But thetrimming all at once can be daunting. I prefer trimming a couple plants a day.
Ideally I would like to have a flower chamber big enough to hold 60 3 gallons so I could add a new plant and trim a plant everyday.
In a perfect world perpetual would work that way, but as our seasons change I swear my girls know and have to have a 'menstrual cycle' and stress right around winter equinox every year. Or, summer has a heat wave.
One every other week is enough for me. I clean the floors every day half-assed and once a month I get down on my hands and knees and get all the webs and crap, bug spray the crevices.
In my condition I don't think I could handle much more.
I always did the perpetual thing. However, I think that you can get better yield and bud in a cycle though. It allows for use of advanced lighting schedules that you can't use when you have plants in various stages of flower in the same room. But, you'll end up needing multiple flower rooms as your new batches of clones are gonna want a home.