Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer

Cannabis-Linked Cell Receptor Might Help Prevent Colon Cancer
Friday, August 1, 2008; 12:00 AM

FRIDAY, Aug. 1 (HealthDay News) -- A cannabinoid receptor lying on the surface of cells may help suppress colorectal cancer, say U.S. researchers. When the receptor is turned off, tumor growth is switched on.
Cannabinoids are compounds related to the tetrahydrocannabinol (THC) found in the cannabis plant.
It's already known that the receptor, CB1, plays a role in relieving pain and nausea, elevating mood and stimulating appetite by serving as a docking station for the cannabinoid group of signaling molecules. This study suggests that CB1 may offer a new path for cancer prevention or treatment.
"We've found that CB1 expression is lost in most colorectal cancers, and when that happens, a cancer-promoting protein is free to inhibit cell death," senior author Dr. Raymond Dubois, provost and executive vice president of the University of Texas M.D. Anderson Cancer Center, said in a university news release.
In their study of human colorectal tumor specimens, the researchers also found that the drug decitabine can restore CB1 expression.
In addition, mice that are prone to developing intestinal tumors and also have functioning CB1 receptors developed fewer and smaller tumors when treated with a drug that mimics a cannabinoid receptor ligand, the researchers found. Ligands are molecules that function by binding to specific receptors.
"Potential application of cannabinoids as anti-tumor drugs is an exciting prospect, because cannabinoid agonists (synthetic molecules that mimic the action of natural molecules) are being evaluated now to treat the side effects of chemotherapy and radiation therapy," DuBois said. "Turning CB1 back on and than treating with a cannabinoid agonist could provide a new approach to colorectal cancer treatment or prevention."
The study was published in the Aug. 1 issue of the journalCancer Research.
More information
The American Cancer Society has more about colorectal cancer.
SOURCE: University of Texas M.D. Anderson Cancer Center, news release, Aug. 1, 2008

I just get my revised list posted up and they come out with another great study! (Big Sigh! ;)) Guess I'll have to get started on next year's version already! lol :D Poor me!


Thanks for posting that! Every bit of info helps! :thumbsup:

Granny:hippy:

I think it's sad that in our nation it's more important to let people suffer and die, because cancer 'treatments and medication' are so expensive.

I'm convinced that some of the compounds and chemicals in marijuana are effective at eliminating cancer as well as alzheimer's...but they'll never let us use anything that can be obtained for next to nothing by growing it, and are effective.

My aunt battled breast cancer, and now, 8 months later she's in so much debt because of it, I certainly know why there's not a cure, and it's not because there isn't one, it's simply because the pharmaceutical industry and medical complex don't want to lose the money they're making. It's a sad sad time in america in this day and age..

You should be doing two things, if you haven't done them already. (1) Go over to IC and read the posts by peanut butter! (2) Print up and give the breast cancer articles in the link below to both your aunt and her doctor.

Granny:hippy:

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Originally Posted by Storm Crow

You should be doing two things, if you haven't done them already. (1) Go over to IC and read the posts by peanut butter! (2) Print up and give the breast cancer articles in the link below to both your aunt and her doctor.

Granny:hippy:

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I've had my aunt read many articles...she's aware that marijuana is most likely the most effective thing for cancer at this point, but she also knows just as well that I do that they don't want people to be able to cheaply acquire safe and effective medication when they can charge what they do for 'treatments'

you all need to see this video!!!! its 7 mini videos RUN FROM THE CURE. THE
RICK SIMPSON STORY... I HOPE EVERYONE VIEWS THIS VIDEOS HEMP OIL CAN CURE CANCER!!!! SPREAD THE WORD BUT NOT ON THIS SITE CUZ I DID AND THEY DELETED MY POST ABOUT THIS VIDEO AND HEMP OIL!!!!!

Quote:

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Originally Posted by dano420

you all need to see this video!!!! its 7 mini videos RUN FROM THE CURE. THE
RICK SIMPSON STORY... I HOPE EVERYONE VIEWS THIS VIDEOS HEMP OIL CAN CURE CANCER!!!! SPREAD THE WORD BUT NOT ON THIS SITE CUZ I DID AND THEY DELETED MY POST ABOUT THIS VIDEO AND HEMP OIL!!!!!

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hey dano nice of you too post,, not sure why it was deleted last nite :wtf:
i have seen the videos and it really makes a point. maybe its the way he makes his hemp oil is why its been deleted, as this is a medical MJ site and that is a medical use of mmj. I also would prefer a better way to make it other using harsh toxic cancer causing chemicals !!!! :mad: