I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
He says that the cigarette company R.J. Reynolds already has a genetically engineered "super pot" in a greenhouse/warehouse. He says they are waiting to release it to the public once marijuana becomes legalized. This makes me think that the myth surrounding G-13 might not be such a myth. He says he and his friend planned to "break in", just to see what this super pot was like, but they said security was so tight that it was virtually impossible.
He told me cannabinol was an alcohol, and part of the high comes from dehydration from the brain. The reason eaten weed has a different high than smoked weed is because it is processed through the liver, which in turn changes the high and length of time it lasts.
He informed me that THC was such a small compound, consisting of carbon, nitrogen, oxygen and hydrogen (I think, I can't remember exactly, but anyone who wants to break apart the name with IUPAC can figure it out) that easily fits through the membrane surrounding the brain, a sort of blood membrane. The cannabinoids go directly into the brain, passing through the membrane that blocks many other chemicals out.
He also started telling me that the "cannibinoid receptors" are not actually "designed" for cannabinoids, per se, but they are reactive to many other chemicals also. The way the cannabinoids react to the receptors is what produces the high.
He is writing a paper on cancer (forgot what he was writing, nothing completely new, though, just reinterpreted research) which states that cancer cells are actually DESTROYED by THC, not just inhibited from growth. He also says though, that it kills many other cells, too.
He notes that the extreme heat from the cannabis smoke is the only thing that really damages the body. The THC is entirely safe (as all of you know). In other words, vaporizing is entirely healthy.
Smoking out of a bong, he says, filters the smoke, but not like most people believe. It does not filter the tar or chemicals, but mostly just the "scoobs" and other tangible smoke. The tar and other chemicals are still there.
He says that cancer researchers have BLOCKS, yes SOLID BLOCKS about a foot in both length, height, and width of SOLID THC that they use for research. You must have a special permit to access these blocks.
We talked alot more, I can't really recall everything, but this just gives you an idea. He was awesome. :thumbsup:
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
Wow.. blocks of THC... ridiculous. Is there a way to synthesize THC? There's gotta be somehow...
But anyhow, that's pretty awesome about the superpot haha. I really should buy a vape, but I dont have the cashmoneys now. Vapes are so much healthier *sigh*
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
Herb likely is not getting legalized anytime soon. lawmakers don't want everyone stoned, they might see the truth about shit that goes on in this country...
the cigarette company making pot rumors have been around a while... "Marlboro Marijuanas"
delta 9 thc is converted by the liver into delta 11, a much more psychoactive form...
solid THC blocks? "and rocking-horse people eating marshmellow pies" i wanna trip whatever you guys were!
:)
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
Quote:
Originally Posted by melodious fellow
Herb likely is not getting legalized anytime soon. lawmakers don't want everyone stoned, they might see the truth about shit that goes on in this country...
the cigarette company making pot rumors have been around a while... "Marlboro Marijuanas"
delta 9 thc is converted by the liver into delta 11, a much more psychoactive form...
solid THC blocks? "and rocking-horse people eating marshmellow pies" i wanna trip whatever you guys were!
:)
I mean, he came and visited our Honors Organic class, he goes to Wake Forest and is graduating with honors in Organic Chem, specifically studying cannabis. I really assume he knows what he's talking about. He is fuckin' smart.
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
most cannaboids are metabolized in the liver, (but some are stored in fat too) it doesnt matter if you smoke it, vape it, eat it, use a transdermal patch, intravenous injection, take it sublingually, or rectally. Delta-9-THC is metabolized to 11-hydroxy-delta-9-THC through all of these methods of administration. 11-hydroxy is then metabolized into 9-carboxy-THC, which is a metabolite; this is what drug tests are designed to look for.
As far as synthetic thc or cannaboids, there are a whole wack of them. One of them is HU-210 (1,1-Dimethylheptyl-11-hydroxytetrahydrocannabinol) which mimics natural thc, but is 100-800x more potent. HU-210 is a full agonost, for the cb1 receptor, where as thc isnt, meaning that every single of thc's effects would be magnified by 100-800 times, making fatal overdoses possible! :(
Yay science.
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
Quote:
Originally Posted by Zonyc
most cannaboids are metabolized in the liver, (but some are stored in fat too) it doesnt matter if you smoke it, vape it, eat it, use a transdermal patch, intravenous injection, take it sublingually, or rectally. Delta-9-THC is metabolized to 11-hydroxy-delta-9-THC through all of these methods of administration. 11-hydroxy is then metabolized into 9-carboxy-THC, which is a metabolite; this is what drug tests are designed to look for.
As far as synthetic thc or cannaboids, there are a whole wack of them. One of them is HU-210 (1,1-Dimethylheptyl-11-hydroxytetrahydrocannabinol) which mimics natural thc, but is 100-800x more potent. HU-210 is a full agonost, for the cb1 receptor, where as thc isnt, meaning that every single of thc's effects would be magnified by 100-800 times, making fatal overdoses possible! :(
Yay science.
Awesome post.
What I meant was that instead of some of the cannabinoids being processed through the liver and some going directly through the brain via bronchioles and capillaries in the lungs, all of the cannabinoids are processed by the liver when eaten.
And although fatal overdoses may seem possible, the amount of marijuana it takes to kill a human has been tried, and tried, and tried again, but still has not determined a significant value. Scientists usually call this the "half-value" (or something like this), where they determine half of the dose of a chemical it takes to produce a lethal effect). I hear the rate of consumption of the highest grade marijuana has is 1.5g every second for fifteen minutes. Which makes me think that even with an ultra-high dose of a synthetic THC compound, it still would not produce a fatal effect, simply because the receptors will just "shut off" if they are overstimulated.
Not saying your wrong, though. I just believe that even by maginification of the high by 800x still would not produce a fatal effect. I'm no scientist though.
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
brand name on the market "Marinol" you can find it in most pharmacies only with a prescription.
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
Quote:
Originally Posted by TPot
Awesome post.
What I meant was that instead of some of the cannabinoids being processed through the liver and some going directly through the brain via bronchioles and capillaries in the lungs, all of the cannabinoids are processed by the liver when eaten.
And although fatal overdoses may seem possible, the amount of marijuana it takes to kill a human has been tried, and tried, and tried again, but it has not hapenned yet.
Not saying your wrong, though. I just believe that even by maginification of the high by 800x still would not produce a fatal effect. I'm no scientist though.
Nothing goes right to the brain without being metabolized, your body doesnt work that way.
While ODing on marijuana isnt humanly possible ( 50-86g in one sitting for a 150lb person), it does have a sedetive effect, and as HU-210 is a full agonist, this sedetive effect would prove to be fatal at just a fraction of those doses.
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
Well you can pretty much bet your bottom dollar that the cigarette companies would take full and utter control of the marijuana industry if it became legal, super weed or not. Most have probally already thought of packaging and other such ventures.
I spoke with an Organic Chemistry major. He smokes weed, and is AWESOME. Read this.
Quote:
Originally Posted by Zonyc
Nothing goes right to the brain without being metabolized, your body doesnt work that way.
While ODing on marijuana isnt humanly possible ( 50-86g in one sitting for a 150lb person), it does have a sedetive effect, and as HU-210 is a full agonist, this sedetive effect would prove to be fatal at just a fraction of those doses.
Oh cool dude, I didn't know that.
Are you a chemist? You seem to know an awful lot.
