No Buzz!!

[lipshitz]

Is there anybody who smokes weed and barely gets stoned? It is a huge problem for me. I smoke and smoke day after night and barely get a buzz. Not so much as a glow :mad: . I've been smoking for over 12 years now. So I know all about quality, etc... (in other words don't post a reply that it's the quality).

The problem got worse last year when I started taking anitdepressants--celexa (citalopram) first then effexor (venlafaxine) From the little bit of info out there and with my own general observations I figured that the antidepressants blocked out the effects of weed!! I have been off those pills for 6 months now but now I think the brain chemistry is all messed up. I cannot get high!!!

Is there anybody else who has the same problem:confused: ? Can you please help :confused: :confused: ? This has driven me insane back then and irritates me now (it is equal to losing a loved one! :cool: ) It is not in my interest to to quit smoking weed :o --the antidepressants actually made me crave it more!

[mafyew]

take a break i guess

[birdgirl73]

I didn't get very high when I smoked, either, and I attributed it to the fact that I wasn't smoking enough, but my sister, who smoked the same amount, was flying. It may just be a difference in your brain chemistry.

I read a depressing fact a couple of weeks ago about long-term cannabis use that I'll try and dig up. It said that the longer people smoke, the less they get the desired effects from cannabis. That is, the highs get lower, and the other thing it said was that, after years of smoking, the negative side-effects (like coughing or irritation or maybe even forgetfulness) get more noticeable.

Maybe take a nice, long, three-month break and see if that helps. If it doesn't, try hash or something stronger.

[Captain Hanks]

I didn't get very high when I smoked, either, and I attributed it to the fact that I wasn't smoking enough, but my sister, who smoked the same amount, was flying. It may just be a difference in your brain chemistry.

I read a depressing fact a couple of weeks ago about long-term cannabis use that I'll try and dig up. It said that the longer people smoke, the less they get the desired effects from cannabis. That is, the highs get lower, and the other thing it said was that, after years of smoking, the negative side-effects (like coughing or irritation or maybe even forgetfulness) get more noticeable.

Maybe take a nice, long, three-month break and see if that helps. If it doesn't, try hash or something stronger.Well of course the "desired effects" become diminished after a period of use because you gain tolerance. I've never heard of a tolerance free drug anyways, but it's a good thing that it's not permanent. You simply need to take a "tolerance break." You say you smoke everday so I would recommend taking a week off. By the end of the week it will almost feel like your first time, for me it does at least. Good luck:rasta:

[lipshitz]

A 3 month break would be a dream. Quitting tobacco was much easier for me and I smoked that crap for nine years!

It's too hard to stop even for a couple of days! I get extremely irritated with people :mad: They wont stop talking about themselves :p . I need a hoot to get through each day. It is medicinal afterall.

I believe brain chemistry is part of the problem. I don't meet very many people who have the same complaint as me. Oh well, I'll quit after this last bag right?? ;)

[birdgirl73]

Well, perhaps this fell under the auspices of "tolerance," but what the article was really talking about was very long-term use over decades and changes to the CB1 and CB2 receptors, neurotransmitters, and neurochemistry that occur over long periods of time, not just familiarity and frequent use of the substance leading to simple tolerance. A good many knowledgeable folks believe "tolerance" where cannabis is concerned is actually a myth.

[lipshitz]

I do believe there has been a change in the neurochemistry. I do not see many aspects of tolerence with myself and weed.
I did hear something about marijuana and the deterioration of the CB1/CB2 receptors. Therefore, I could be smoking all this weed but no specific receptors to catch the psychoactive molecules :confused: ? Possible, but I could be rambling on.

[Inferius]

Depressing. They need to invent alternative soft core drugs like cannabis.

[trem0lo]

Tolerance is most definitely not a myth... Switching strains helps, but after a few weeks of smoking everyday, I definitely notice a difference in the intensity of my highs.

Then I take a week off, and boom... tolerance reset!