Physiological differences in Sativa/Indica stains

[willystylle]

Are there any?

I've noticed that I only get red-eye when I smoke Sativa strains. Indica strains have no effect on my eyes. The same applies to my speech, coordination, etc. Anyone else noticed this? Or could it be a biological thing?

[Breukelen advocaat]

Are there any?

I've noticed that I only get red-eye when I smoke Sativa strains. Indica strains have no effect on my eyes. The same applies to my speech, coordination, etc. Anyone else noticed this? Or could it be a biological thing?

I'd be glad to test this theory out if you'll send some samples. :dance:

[1234abcd]

I'd be glad to test this theory out if you'll send some samples. :dance:

LOL


I think your talking out BS, and you really dont know what your eyes look like. Take a look at the mirror next time you smoke an indica, and I guarantee you if you took a big enough rip, your eyes will go red on the outter part of them. The thing is, us stoners dont realize that our eyes are squinty and red, because we feel great when we're high, and really dont give a shit. If you are worried about the redness, just put a cleareye drop in each eye, and they will look way more white, and you will appear completely sober even tho you are totally fucked up. Also get gum for your breath, and wash the sticky icky off your finger tips, unless your lucky enough to have bought a nice hERb grinder..Damn I need one, but the one I want is 45..and damn .thats kinda alot for an herb grinder..maybe I can find it on ebay or something for cheaper but then I can't see what Imgetting

Well anyways I started bird walking because I type so fast, but to get back to topic, sativas tend to make me more wound up, while indicas help me relax, but ALL in ALL, if I take a big enough rip of either or, my eyes will get red. 420 4 LIFE

Also the redness is a good sign of how marijuana can help out medical ailments, for example people with Glaucoma (eye pressure) , smoke MJ, and it makes their eyes get bloodshot, while relaxing them , and relieving pressure..that is all that is happening when they are red..is that your brain is releasing pressure from the THC you just smoked...therefor redness occurs...and this happens with ALL potent flowers, hashish, oil, everything MJ!

[beachguy in thongs]

Are there any?

I've noticed that I only get red-eye when I smoke Sativa strains. Indica strains have no effect on my eyes. The same applies to my speech, coordination, etc. Anyone else noticed this? Or could it be a biological thing?

Leave it to good, old Erowid.
http://www.erowid.org/plants/cannabis/cannabis_info6.shtml

Although, that link, I'm not sure, will answer your question.

[willystylle]

Thanks for the posts and thanks beachguy for the link... but sorry it didn't help.

What I mean is does anyone notice any differences in red-eye, cottonmouth and all the other shit when smoking different strains? I strongly believe that the indica strain does not give me red eyes while sativa strains do.

I don't bother with red-eye even when I have it - I just tell people dust/allergies/crying whatever and thats the end of it - but it would be interesting to note if anyone else has the same symptoms.

and 1234abcd, I do look in the mirror, its one of my weird habits when I get high, and no offence here but I think I know what I'm talking about as I'm describing myself.

[beachguy in thongs]

Another reason that your eyes can get bloodshot is lack of sleep. You can switch up your excuses, every once in a while.

[beachguy in thongs]

Okay, willy, I'll try and throw this out there. Maybe, someone else can help.

CB1 receptors have been detected in the retinas of numerous species, including salamander, goldfish, chick, rat, mouse, monkey, and human (Straiker et al. 1999a,b; Yazulla et al. 1999).

CB2 receptors are mainly in your immune system. That may be the target of Indicas, I don't know.

[THE MEDIC]

Okay, willy, I'll try and throw this out there. Maybe, someone else can help.

CB1 receptors have been detected in the retinas of numerous species, including salamander, goldfish, chick, rat, mouse, monkey, and human (Straiker et al. 1999a,b; Yazulla et al. 1999).

CB2 receptors are mainly in your immune system. That may be the target of Indicas, I don't know.
beachguy, do you mean like...CB2/immunesystem/bodyhigh/indicas...CB1/retina-brain../headhigh/sativas???

This is from the...Behavioral effects of cannabinoid agents in animals
by
Chaperon F, Thiebot MH

"Most of the agonists exhibit nonselective affinity for CB1/CB2 receptors, and delta9-THC and anandamide probably act as partial agonists. Some recently synthesized molecules are highly selective for CB2 receptors, whereas selective agonists for the CB1 receptors are not yet available. A small number of antagonists exist that display a high selectivity for either CB1 or CB2 receptors."


I know its animals ,but.....
will goldfish eat bud??theres always a bud ready to eat your goldfish :D
http://www.cannabis.net/cb1/index.html

[THE MEDIC]

Are there any?

I've noticed that I only get red-eye when I smoke Sativa strains. Indica strains have no effect on my eyes. The same applies to my speech, coordination, etc. Anyone else noticed this? Or could it be a biological thing?

I get red-eye no matter what strain I,m smoking....coughing, choking and a general taste of crap in my mouth came from some ill prepared (HOLY SHITTT their turning YELLOW!!!!!SPRAY'M!!!QUICK!!!) to the just plan ''I dont care how it comes out as long as it sells" kinda buds...they all gave me red-eye:stoned:

Indicas affect my eyes by keeping them closed:) thats why I wear shades...:cool:

[beachguy in thongs]

beachguy, do you mean like...CB2/immunesystem/bodyhigh/indicas...CB1/retina-brain../headhigh/sativas???

This is from the...Behavioral effects of cannabinoid agents in animals
by
Chaperon F, Thiebot MH

"Most of the agonists exhibit nonselective affinity for CB1/CB2 receptors, and delta9-THC and anandamide probably act as partial agonists. Some recently synthesized molecules are highly selective for CB2 receptors, whereas selective agonists for the CB1 receptors are not yet available. A small number of antagonists exist that display a high selectivity for either CB1 or CB2 receptors."

I know its animals ,but.....
will goldfish eat bud??theres always a bud ready to eat your goldfish :D
http://www.cannabis.net/cb1/index.html


Yes, sort of, although CB1 receptors are found throughout the body (this 2002-released study says "expressed primarily in the brain and in some peripheral tissues" (Howlett et al., 2002; Pertwee and Ross, 2002)). CB2 "mainly" in the immune system.

This study does show a difference between the two receptors by administering a CB1 receptor antagonist and it did not affect the effects of the Cannabidiol:


The addition of CBD to the culture medium led to a dramatic drop of mitochondrial oxidative metabolism [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H tetrazolium bromide test] and viability in glioma cells, in a concentration-dependent manner that was already evident 24 h after CBD exposure, with an apparent IC50 of 25 µM. The antiproliferative effect of CBD was partially prevented by the CB2 receptor antagonist N-[(1S)-endo-1,3,3-trimethylbicyclo[2,2,1]heptan-2-yl]-5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)-pyrazole-3-carboxamide (SR144528; SR2) and {alpha}-tocopherol. By contrast, the CB1 cannabinoid receptor antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboximide hydrochloride (SR141716; SR1), capsazepine (vanilloid receptor antagonist), the inhibitors of ceramide generation, or pertussis toxin did not counteract CBD effects. We also show, for the first time, that the antiproliferative effect of CBD was correlated to induction of apoptosis, as determined by cytofluorimetric analysis and single-strand DNA staining, which was not reverted by cannabinoid antagonists.

First published on November 14, 2003

As with all studies, as a community, further research on this subject is suggested. Right now, I'm hot and have to turn up my air.

[THE MEDIC]

I do understand the importance of cancer cell research...Malignant gliomas are the most common type of brain tumor ... many neurodegenerative diseases are characterised by oxidative stress-induced damage so yes... more research is nessesary..on these lines and many others...I read an articule that I liked and understood..so I posted it...sorry if it got hot from the passing air...


BTW...Revised Oct 3 2003
Finally, CBD, administered s.c. to nude mice at the dose of 0.5 mg/mouse, significantly inhibited the growth of subcutaneously implanted U87 human glioma cells..

peace..

[beachguy in thongs]

Medic, you mean the link that you posted? Why apologize? It was from 1999 and that was around the time that the U.S. and Europe were doing studies on it, and still haven't released them to the public.

When I was told that, he (drug expert, who proclaimed his main expertise was "pot"), also, told me about the Cancer Cure proof that the government found out about, in the 1970's, and, he these were his exact words, "You know, the U.S. and Europe are doing studies on it, right now. All good. All the studies (are coming up) positive. (They can't find anything wrong with it.) Expect them to make their findings public within the next five to ten years."

[THE MEDIC]

I didnt study long enough to make a profession out of biochem..just a hobby:D

if by any chance you are deep into it , I'm sure this person would love to discuss it with you..
Daniela Parolaro, Dept. of Structural and Functional Biology, Pharmacology Unit and Center of Neuroscience, University of Insubria, Via A. da Giussano 1021052 Busto Arsizio (Varese), Italy.
[email protected]

peace..

[beachguy in thongs]

Thanks, medic. It's another lead. Italian scientists are the ones who made the 4,000% melatonin-boost discovery, twenty years ago.

[beachguy in thongs]

I just wanted to add a piece of information that, I think, is an act of God.

Or, whoever the hell you want to say "made us".

That cannabinoid receptors are one of the most numerous in our Nervous System.

And why don't we have Apple & Orange Receptors?

[THE MEDIC]

beachguy,Everything we need is there,filed away in our DNA...generations upon generations of the recording of how the the body/mindhas/will adapte....and then with out any order give by the brain ...its stored and then passes it down....Beautiful...simply...Beautiful!! THe deeper we decend the smaller we go..the more we're Amazed.... No way this is random.

ALL thats missing is an interface between gene&machine....
ALL that Knowledge...so little time..:( time??ohya..

ALL info will be used for Good....or trivial pursuit:dance:

[beachguy in thongs]

Our webs grew into our hands, the ones we used for swimming, and our second eyelid, the one we used to keep water out, grew into a ball in the corner of our eye. What's gonna happen to our CB1 and CB2 receptors if we don't activate them to their fullest potential?

A long time ago, when we were cavemen, wouldn't you think that we were tougher and stronger? When we couldn't even walk upright, don't you think we were similar to deer in Asia, who eat a strain that grows high in the mountains? Obviously, we prefer it, this late in evolution.

It may have been a totally different animal.

[THE MEDIC]

webs into hands...second eyelids..hmm..ok

I still like our bodies harddrive:smokin:

[beachguy in thongs]

LOL, maybe that didn't come out right.

I meant, the webs of our hands grew in. And, where our tear duct is, I learned, somewhere, that we were ancestors of the crocodile, which has two eyelids, and not the alligator, which only has one.

[THE MEDIC]

if you dont mind beachguy I'll just file that in the "Ripley'sBelieve it or not"drawer....I've been told outright...YOU came from Chimps..well I do like to scratch myself but come on...I draw the line at having a croc in my family tree...

our genetics hold counless bits of information..just not the anwser...:)

[beachguy in thongs]

If we did come from chimps, chimps came from crocs, which came from fish.

But, for some reason, I'm don't think that we came from chimps. I heard of a commonly thought of ancestor, of Ours, being discovered that it was not in our past.

Hypothesis #1: Chimps are not our ancestors.

I'm basing that decision on the fact that we're talking about chimps and I can't think of another species that might fit that criteria.

Yeah, I just saw one, and came to the conclusion that I'm nuts.

[S8ted]

LOL


I think your talking out BS, and you really dont know what your eyes look like. Take a look at the mirror next time you smoke an indica, and I guarantee you if you took a big enough rip, your eyes will go red on the outter part of them. The thing is, us stoners dont realize that our eyes are squinty and red, because we feel great when we're high, and really dont give a shit. If you are worried about the redness, just put a cleareye drop in each eye, and they will look way more white, and you will appear completely sober even tho you are totally fucked up. Also get gum for your breath, and wash the sticky icky off your finger tips, unless your lucky enough to have bought a nice hERb grinder..Damn I need one, but the one I want is 45..and damn .thats kinda alot for an herb grinder..maybe I can find it on ebay or something for cheaper but then I can't see what Imgetting

Well anyways I started bird walking because I type so fast, but to get back to topic, sativas tend to make me more wound up, while indicas help me relax, but ALL in ALL, if I take a big enough rip of either or, my eyes will get red. 420 4 LIFE

Also the redness is a good sign of how marijuana can help out medical ailments, for example people with Glaucoma (eye pressure) , smoke MJ, and it makes their eyes get bloodshot, while relaxing them , and relieving pressure..that is all that is happening when they are red..is that your brain is releasing pressure from the THC you just smoked...therefor redness occurs...and this happens with ALL potent flowers, hashish, oil, everything MJ!

www.vaporstore.com has some nice grinders, & good prices.

[S8ted]

If we did come from chimps, chimps came from crocs, which came from fish.

But, for some reason, I'm don't think that we came from chimps. I heard of a commonly thought of ancestor, of Ours, being discovered that it was not in our past.

Hypothesis #1: Chimps are not our ancestors.

I'm basing that decision on the fact that we're talking about chimps and I can't think of another species that might fit that criteria.

Yeah, I just saw one, and came to the conclusion that I'm nuts.

the book 'The Medicine Way'(forgot the author) talks about human ancestry, according to Native Americans. A wonderful read in my opinion.

[beachguy in thongs]

the book 'The Medicine Way'(forgot the author) talks about human ancestry, according to Native Americans. A wonderful read in my opinion.

Cool.

I searched it on tfd.com and it came up with this:
Some articles that match your query:
alternative medicine - List of medical schools - List of medical schools in the U.S. - List of terms and concepts used in alternative medicine - medicine - Schools of veterinary medicine - sports medicine - Traditional Chinese medicine - History of medicine - medical specialty - Complementary and alternative medicine - Regulation of therapeutic goods - Allopathic medicine - internal medicine - osteopathy