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tadaa
04-10-2006, 06:17 PM
http://en.wikipedia.org/wiki/Marijuana

Since it was ignored in the old thread, I'll post it here.

Tons of sources for you to get your hands on, now quit your bitching.

grinthenbearit
04-10-2006, 06:38 PM
side effects for me included my mother stealing my weed.

friendowl
04-10-2006, 06:44 PM
side effects for me

turning a non smoking girl into a chronic freak

Ripper
04-10-2006, 07:07 PM
Increased or decreased sexual pleasure

Hmmmmmm never decreased.....in my case anyway.

Ap0c4lyPtIcF4t3
04-10-2006, 07:12 PM
side effects? yeah a fuckin empty fridge and ash burns on my goddamn carpet!

tadaa
04-10-2006, 10:40 PM
Where's everyone from the old thread?

beachguy in thongs
04-10-2006, 11:00 PM
Well, ta-fucken-daa. Possible tolerance? Gain, or loss of inhibitions? What they're not sure?

That still uses a study done in 1992.

Read:

MARIJUANA TOLERANCE: EQUILIBRIUM, NOT ADDICTION

Research into drug tolerance is in its infancy. There are actually three forms of tolerance. Dispositional tolerance is produced by changes in the way the body absorbs a drug. Dynamic tolerance is produced by changes in the brain caused by an adaptive response to the drug's continued presence, specifically in the receptor sites affected by the drug. Behavioral tolerance is produced by familiarity with the environment in which the drug is administered. "Familiarity" and "environment" are two alternative terms for what Timothy Leary called "set" and "setting" - the subjective emotional/mental factors that the user brings to the drug experience and the objective external factors imposed by their surroundings. Tolerance to any drug can be produced by a combination of these and other mechanisms.

Brain receptor sites act as switches in the brain. The brain's neurotransmitters, or drugs which mimic them, throw the switches. The basic theory of tolerance is that repeated use of a drug wears out the receptors, and makes it difficult for them to function in the drug's absence. Worn-out receptors were supposed to explain the connection of tolerance to addiction. This phenomenon has been associated with chronic use of benzodiazepines (Valium, Prozac, etc.), for example, but not with cannabinoids.

An alternative hypothesis about how dynamic tolerance to marijuana operates involves receptor "down-regulation," in which the body adjusts to chronic exposure to a drug by reducing the number of receptor sites available for binding. A 1993 paper published in Brain Research by Angelica Oviedo, John Glowa and Herkenham indicates that tolerance to cannabinoids results from receptor down-regulation. This, as we shall see, is good news. It means that marijuana tolerance is actually the brain's mechanism to maintain equilibrium.

I had made a way better post, but the server was busy and erased it on me. I had pointed out that those studies mean nothing to prove your point.

beachguy in thongs
04-10-2006, 11:05 PM
Addictive drugs affect behavior through their effects on the brain "reward system" - the production of dopamine, linked to the pleasure sensation. This brain "reward system" has a powerful influence over behavior. Dependence-producing drugs - drugs that, unlike marijuana, affect dopamine production - eventually exert more influence on the user's behavior than any other factor. The effect of addiction on behavior is so profound as to create a condition called denial, in which someone will say or do anything to continue access to the drug.

Denial is a characteristic of drug abuse, and it is largely cultivated by the effects of various drugs on the brain reward system. Herkenham's research provides a clinical basis for claims that denial is not a characteristic of marijuana use.

Drolover
04-10-2006, 11:38 PM
side effects? yeah a fuckin empty fridge and ash burns on my goddamn carpet!
Same here bro:rasta:

beachguy in thongs
04-11-2006, 02:21 PM
Sorry, that I forgot to post a reference to that link, above:
http://www.pdxnorml.org/brain2.html