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02-07-2006, 12:04 AM
Methods
Fifty-two men aged less than 60 years presenting consecutively with transitional cell carcinoma and 104 age-matched controls (defined by having no history of transitional cell carcinoma, hematuria, or irritative voiding symptoms, as well as unremarkable results on urinalysis and urine cytology) completed questionnaires about exposure to various potential carcinogens, including radiation, Agent Orange, smoked or processed meats, dyes, tobacco, marijuana.
Results
Of the 52 transitional cell carcinoma patients, 46 (88.5%) reported a history of habitual marijuana usage, and 72 (69.2%) of the age-matched controls gave a history of habitual marijuana use. This difference was statistically significant (P = 0.008). In those with transitional cell carcinoma, marijuana use significantly correlated with tumor stage, grade, and number of recurrences.
Conclusions
Marijuana smoking might increase the risk of transitional cell carcinoma.
http://www.sciencedirect.com/science?_ob=ArticleURL&_aset=V-WA-A-W-W-MsSAYWW-UUW-U-AAVAYWUVYE-AABEVUAWYE-ZBDYZVUYD-W-U&_rdoc=1&_fmt=summary&_udi=B6VJW-4J1J57H-S&_coverDate=01%2F31%2F2006&_cdi=6105&_orig=search&_st=13&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=5941895105a39eaee0c6e0c112d8a2bc
Fifty-two men aged less than 60 years presenting consecutively with transitional cell carcinoma and 104 age-matched controls (defined by having no history of transitional cell carcinoma, hematuria, or irritative voiding symptoms, as well as unremarkable results on urinalysis and urine cytology) completed questionnaires about exposure to various potential carcinogens, including radiation, Agent Orange, smoked or processed meats, dyes, tobacco, marijuana.
Results
Of the 52 transitional cell carcinoma patients, 46 (88.5%) reported a history of habitual marijuana usage, and 72 (69.2%) of the age-matched controls gave a history of habitual marijuana use. This difference was statistically significant (P = 0.008). In those with transitional cell carcinoma, marijuana use significantly correlated with tumor stage, grade, and number of recurrences.
Conclusions
Marijuana smoking might increase the risk of transitional cell carcinoma.
http://www.sciencedirect.com/science?_ob=ArticleURL&_aset=V-WA-A-W-W-MsSAYWW-UUW-U-AAVAYWUVYE-AABEVUAWYE-ZBDYZVUYD-W-U&_rdoc=1&_fmt=summary&_udi=B6VJW-4J1J57H-S&_coverDate=01%2F31%2F2006&_cdi=6105&_orig=search&_st=13&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=5941895105a39eaee0c6e0c112d8a2bc