how long for your tolerance...

[kdizzle384]

to be at 0. Caused i stopped for a week and im about to blaze and im just wondering. Tell me if you get what im talking about

[beachguy in thongs]

Just smoke. You'll know.

[NoosaHeads]

to be at 0. Caused i stopped for a week and im about to blaze and im just wondering. Tell me if you get what im talking about



Smoke 3 FAT bowls in a row and if your not chunked then find a new supplier.
:stoned:

[kdizzle384]

thx guys :) im gonna go blaze now :rasta: :rasta: :stoned: :stoned:

[Rarrr]

For your tolerance to be 0 you would have to completely eliminate cannabis from your system

[mrdevious]

I've gone off for a month and a half and my tolerance still dropped only somewhat. I don't think you can ever go back to those days when you first smoked and just got shitfaced like nothing else.

[beachguy in thongs]

Check out this site:
http://www.pdxnorml.org/brain2.html

It's from "High Times", written by Jon Gettman.

Here's a piece:

TOLERANCE, DEPENDENCE AND DENIAL

Herkenham's earlier research mapping the locations of the cannabinoid brain-receptor system helped establish scientific evidence that marijuana is nonaddictive. This new tolerance study builds on that foundation by explaining how cannabinoid tolerance supports rather than contradicts that finding.

"It is ironic that the magnitude of both tolerance (complete disappearance of the inhibitory motor effects) and receptor down-regulation (78% loss with high-dose CP-55,940) is so large, whereas cannabinoid dependence and withdrawal phenomena are minimal. This supports the claim that tolerance and dependence are independently mediated in the brain."

In other words, tolerance to marijuana is not an indication that the drug is addictive.

Norman Zinberg, in 'Drug, Set and Setting' (Yale, New Haven, CT, 1984), explained that the key to understanding the use of any drug is to realize that three variables affect the situation: drug, set and setting. It is now a scientific finding that the pharmacological effects of marijuana do not produce dependency. The use and abuse of marijuana is a function of behavior - interrelated psychological and environmental factors.

Addictive drugs affect behavior through their effects on the brain "reward system" - the production of dopamine, linked to the pleasure sensation. This brain "reward system" has a powerful influence over behavior. Dependence-producing drugs - drugs that, unlike marijuana, affect dopamine production - eventually exert more influence on the user's behavior than any other factor. The effect of addiction on behavior is so profound as to create a condition called denial, in which someone will say or do anything to continue access to the drug.

Denial is a characteristic of drug abuse, and it is largely cultivated by the effects of various drugs on the brain reward system. Herkenham's research provides a clinical basis for claims that denial is not a characteristic of marijuana use.

[anycraic]

but yeah 3 - 6 weeks can do it sometimes, i went without once for 4 moths (not by choice) and that seemed to do the trick for a while

[PureEvil760]

The dose of THC used in the study was 10 mg per kilogram of body weight, a dose frequently used in clinical research. What is the equivalent of 10 mg/kg of THC in terms of human consumption?

The minimum dose of THC required to get a person high is 10 micrograms per kilogram of body weight. For a 165-pound person, this would be 750 micrograms of THC, about what is delivered by one bong hit.

The THC doses used on the NIMH rats were proportionately ten times greater than what a heavy human marijuana user would consume in a day. Assuming use of good-quality, 7.5% THC sinsemilla, it would take something like 670 bong hits or 100 joints to give a 165-pound person a 10 mg-per-kg dose of THC.

..lol

[Reefer Rogue]

I'd say a month max will have you at 0 tolerance.

[pabloescobar209]

It's all common sense...If you smoke less weed per session, and less weed in general or no weed, your tolerance drops... if you smoke more weed per session, and or more weed in general your tolerance goes up.