TheSmokingMonkey
04-09-2008, 02:21 AM
The effect of mini-dose aspirin on renal function ...[Arthritis Rheum. 2000] - PubMed Result (http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&list_uids=10643705&cmd=Retrieve&indexed=google)
I just found this abstract clarifying why aspirin is used in the dilution method. You can read it in "science-ese" at the link, but basically large doses of aspirin cause the body to excrete more uric acid.
I don't know if uric acid is tested and if it is, how wide the range of "normal" might be, but I am certain this is why the dilution method calls for aspirin in twice the recommended dose.
Does anyone know what the ranges are for the test?
"Aspirin is known to have a bimodal effect on the renal handling of uric acid (UA). High dosages (>3 gm/day) are uricosuric, while low dosages (1-2 gm/day) cause UA retention." (from above article)
I just found this abstract clarifying why aspirin is used in the dilution method. You can read it in "science-ese" at the link, but basically large doses of aspirin cause the body to excrete more uric acid.
I don't know if uric acid is tested and if it is, how wide the range of "normal" might be, but I am certain this is why the dilution method calls for aspirin in twice the recommended dose.
Does anyone know what the ranges are for the test?
"Aspirin is known to have a bimodal effect on the renal handling of uric acid (UA). High dosages (>3 gm/day) are uricosuric, while low dosages (1-2 gm/day) cause UA retention." (from above article)